Profile
Yinlong Cai
Lab Manager & Research Assistant
aa9873@wayne.edu
MS, Nanjing Medical College, 1988
To further characterize human platelet 12-lipoxygenase interaction with the integrin subunit B4 functionally and physically. To determine the effects of 12-LOX inhibitors and 12(S)-HETE on hemidesmosome in prostate cancer and A431 cells. To study the signal transduction pathway(s) that underlie the disassembly/assembly of hemidesmosome by 12(S)-HETE or 12-LOX activity and B4 integrin in PC-3 cells and A431 cells.
aa9873@wayne.edu
Education
MD, Nanjing Medical College, 1983MS, Nanjing Medical College, 1988
Project & Aims
Role of Eicosanoids in Tumor Cell MetastasisTo further characterize human platelet 12-lipoxygenase interaction with the integrin subunit B4 functionally and physically. To determine the effects of 12-LOX inhibitors and 12(S)-HETE on hemidesmosome in prostate cancer and A431 cells. To study the signal transduction pathway(s) that underlie the disassembly/assembly of hemidesmosome by 12(S)-HETE or 12-LOX activity and B4 integrin in PC-3 cells and A431 cells.




