School of Medicine

Wayne State University School of Medicine
K.V. Honn Cancer & Metastasis Research Group
Department of Pathology

Profile

Yinlong Cai

Lab Manager & Research Assistant
aa9873@wayne.edu

Education

MD, Nanjing Medical College, 1983
MS, Nanjing Medical College, 1988

Project & Aims

Role of Eicosanoids in Tumor Cell Metastasis

To further characterize human platelet 12-lipoxygenase interaction with the integrin subunit B4 functionally and physically. To determine the effects of 12-LOX inhibitors and 12(S)-HETE on hemidesmosome in prostate cancer and A431 cells. To study the signal transduction pathway(s) that underlie the disassembly/assembly of hemidesmosome by 12(S)-HETE or 12-LOX activity and B4 integrin in PC-3 cells and A431 cells.