Profile
Sen-Lin Zhou
Research Assistant
zhous@wayne.edu
Development of synthetic procedure(s) for glucuronides of BMD122 and BMD188. In vitro characterization of BMD122 and BMD188 glucuronides for biological activity against prostate cancer cells. Development and validation of HPLC methodology for BMD122, BMD188, and their glucuronides. Pharmacokinetics of BMD122 anad BMD188 glucuronides in normal rats and in mice harboring prostate carcinoma xenografts.
zhous@wayne.edu
Education
BSc, Shanghai Medical University, 1982Project & Aims
Anticancer Prodrug Development ProgramDevelopment of synthetic procedure(s) for glucuronides of BMD122 and BMD188. In vitro characterization of BMD122 and BMD188 glucuronides for biological activity against prostate cancer cells. Development and validation of HPLC methodology for BMD122, BMD188, and their glucuronides. Pharmacokinetics of BMD122 anad BMD188 glucuronides in normal rats and in mice harboring prostate carcinoma xenografts.